Wednesday, 10 December 2014

PHARMACEUTICS- Heart Of Pharmacy- Part- II

                                           PHARMACEUTICS- Heart Of Pharmacy-
                                                                        Part II
In the previous post, we covered about some basic concepts in subjects like Physical Pharmacy, Dispensing Pharmacy and Pharmaceutical Engineering, which are essential beforehand in order to start our actual "PHARMACEUTICS" preparation.
In this post we will actually cover the guidance about actual subject- PHARMACEUTICS and its allied courses which are also important like 'Community Pharmacy / Hospital Pharmacy and Drug Store Management' and 'Biopharmaceutics and Pharmacokinetics'.
PHARMACEUTICS- This subject, as we are well aware of, deals with the science behind various dosage forms ranging from liquid orals, semi-solid dosage forms to solid dosage forms like tablets, capsules till parenteral products. A lot many questions can be asked on this subject. Typical questions asked will be discussed chapter-wise below.
COMMUNITY PHARMACY / HOSPITAL PHARMACY AND DRUG STORE PHARMACY-
From this topic hardly any questions are asked. Maximum 2-3 questions. But a general knowledge about the role of pharmacist in drug store and hospitals, working and management of hospital and its services should be remembered.
BIOPHARMACEUTICS AND PHARMACOKINETICS- Biopharmaceutics particularly focuses more on the changes we need to make in the dosage form to increase bioavailability; whereas pharmacokinetics deals with what happens to the drug once it is inside in the body. Minimum 1-2 numerical problems are definitely asked from this subject about bioavailability, plasma drug concentration kinetics such as calculation of tmax, Cmax, AUC (Area Under the Curve) etc. So even if you are not much thorough with theoretical knowledge of these subjects, concepts must be clear regarding numerical calculations of pharmacokinetics. There should not be any confusion in remembering the formulaes. Try to practice as much as you can regarding all numerical problems as these are easy gains during the GPAT exam if the formulas are crystal clear in your mind.
 (NOTE- Calculators are not allowed during GPAT examination, so it is very much essential that you should try to practice numerical problems WITHOUT calculators or atleast you should be able to approximately predict the nearest correct answer.
In GATE examination, calculators are allowed... This is another plus point in GATE exam)

Books recommended for studying-
1. Leon Lachman and Herbert A. Lieberman, " The Theory and Practice of Industrial Pharmacy", Special Indian Edition, CBS Publishers and Distributors Pvt Ltd., 2009.

2. David B. Troy, Paul Beringer, "Remington ; The Science and Practice of Pharmacy", Lippincott Williams and Wilkins, 2006.

3. S.J. Carter, "Cooper and Gunns Tutorial Pharmacy",1st Edition, CBS Publishers, 2005.

4. P.P. Sharma, "Cosmetics- Formulations, Manufacturing & Quality Control", 3rd Edition, Vandana Publications Pvt. Ltd., 2005.

5. J.B. Wilkinson & R.J. Moore, "Harry's Cosmeticology", 7th Edition, Longman Singapore Publishers Pvt. Ltd.

6. Dr. H.P. Tipnis and Dr. Amrita Bajaj, "Hospital Pharmacy", Career Publications, 2008.

7. Leon Shargel, Sussana Wu-Pong, Andrew Yu, "Applied Biopharmaceutics and Pharmacokinetics", 6th Edition, McGraw Hill Professional Publishers, 2012 (RECOMMENDED FOR PHARMACOKINETICS).

8. D.M. Brahmankar,  Sunil B. Jaiswal, "Biopharmaceutics and Pharmacokinetics- A Treatise", 2nd Edition, Vallabh Prakashan/ Publishers (RECOMMENDED FOR BIOPHARMACEUTICS).

PHARMACEUTICS (In GPAT syllabus they have mentioned under the heading- Dosage Forms, designing & evaluation)

1.Liquid Dosages Forms: 1,2 (Remember various ingredients and its properties).

2.Semisolid Dosage Forms: 1,2 (Stress more on ointment bases, creams and gels).

3. Suppositories: 1 (Focus on suppository bases and its properties)

4. Extraction and Galenical Products: 2

5. Blood Products and Plasma Substitutes: 3

6. Pharmaceutical Aerosols: 1 (Stress more on the evaluation tests, its temperatures and pressures, nomenclature of propellants and various parts of aerosol container)

7. Ophthalmic Preparations: 2 (Stress more on labelling conditions, preservatives and other formulation aspects of ophthalmic products)

8. Cosmeticology and Cosmetic Preparations: 4,5 (Focus more on formulation and evaluation of lipstick, nail paints, dental products and skin car products).

9. Capsules: 1 (Remember the capsule sizes and the corresponding volumes)

10. Micro-encapsulation: 1

11. Tablets: 1 (Almost everything is important from this topic)

12. Parenteral Products: 2 (Same applies as that of tablets)

13. Surgical products: 2, 3

14. Packaging of Pharmaceutical Products: 1,2 (Try to remember which conatainer and which packing material is used for that particular dosage form).

15. Designing of dosage forms: 1 (Important topic, too !!)

16. Performance evaluation methods: 8 (Remember the I.P, B.P, U.S.P dissolution apparatus types and its application for that particular dosage form).

HOSPITAL PHARMACY AND DRUG STORE MANAGEMENT

1. Community Pharmacy: 2,6

2. Organization and Structure of hospital pharmacy: 2,6

3. Hospital Formulary: 2,6

4. Drug Store Management and Inventory Control: 2,6

5. Drug distribution Systems in Hospitals: 2,6

6. Central Sterile Supply Unit and their Management: 2,6

7. Manufacture of Sterile and Non-sterile Products: 2,6

8. Drug Information Services: 2,6

9. Records and Reports: 2,6

10. Nuclear Pharmacy: 2

BIOPHARMACEUTICS AND PHARMACOKINETICS

1. Introduction to biopharmaceutics: 8

2. Pharmacokinetics: 7,8

3. Clinical Pharmacokinetics: 7,8

4. Bioavailability and bioequivalence: 7,8

This was all for today. Here we complete our guidance about PHARMACEUTICS !! In the next week ,i.e, 17th December 2014, we will start PHARMACEUTICAL MEDICINAL CHEMISTRY guidance section.
Hope you would have liked this part...!!! Any kind of feedback and suggestions are most welcome to our team.
                                                                                          -Darwin
                                                                  [GPAT-2014- All India Rank (AIR)- 619)
                                                                        NIPER-JEE-2014 AIR-25 and
                                                                          ICT-BPT-CET-2014 AIR-7 ]
                                               Ist year M, Tech (Bioprocess Technology-BPT)-2014-16,
                                                      Institute of Chemical Technology, Matunga, Mumbai
                                                 (WITH INPUTS FROM 'CURIE'- GPAT-2014 QUALIFIED)


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